The short answer: Maybe.
A report was presented at a conference in Pennsylvania on Rectal Microbicides that stated that doing tests on some lubricants have shown that they have a high toxicity rate that has increased the breakdown of the integrity of cells in the mucosal lining of both vaginal and anal walls.
The short of it. Astroglide has been shown to be the most toxic lubrication and shown to be on the same degree of toxicity as the dreaded Spermicide, Nonoxynol-9.
For a synopsis of the multiple articles that have been released on this as well as media reports, go to HERE.
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